The most highly conserved protein is PtHSP02-6, a G-protein ß-subunit containing a conserved WD-40 repeat motif.
These analyses indicated that most highly conserved miRNAs avoid G in potentially toxic seed positions.
The most highly conserved portion of the c-Myb protein is the DNA-binding domain which consists of three imperfect repeats.
The most highly conserved noncoding elements (HCNEs) in mammalian genomes cluster within regions enriched for genes encoding developmentally important transcription factors (TFs).
The nucleosome is made up of proteins known as histones, which are among the most highly conserved in evolution, meaning that they change very little from one species to another.
The two overlapping p63 motifs within the 520-bp BSKO region were targeted with two gRNAs to mutate the four highlighted nucleotides —the most highly conserved nucleotides within the canonical predicted p63 binding motif.
The most highly conserved sequence of a putative binding site among various species is located in exon 4 of the low-density lipoprotein receptor adapter protein 1 (LDLRAP1) (Figure 3A).
Calmodulin (CaM) is one of the most highly conserved molecules.
Human INO80 complex is one of the most highly conserved chromatin remodelers.
In plants, the alcohol dehydrogenase gene (Adh1) has been reported to be one of the most highly conserved genes [10, 11, 41].
The sequence also showed high homologous with other characteristic conserved elements of glutathione peroxidases, including the most highly conserved metal ion-binding motif of ILAFPCNQF.
