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Some of the most highly altered genes in this study are involved in signal transduction and general stress response.
The most highly altered canonical pathways were related to the "coagulation system", including "intrinsic" and "extrinsic" "prothrombin activation pathways".
A listing of the functionally annotated genes which are most highly altered is provided in Table 2.
In fact, hypothetical genes account for ~50% of the most highly altered genes between two conditions (Additional file 1: Table S2).
The most highly altered genes at 0.5 and 1.5 dpc are listed in Tables 1 and 2, respectively; representative genes were validated using real-time PCR.
Within the remaining probes, 335 genes were up- or down-regulated ≥ 2-fold; the most highly altered genes are shown in Table 1.
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Our results indicate that fresh, autochthonous organic matter is the most important contributor to base-hydrolyzable lipids, whereas highly altered allochthonous sources appear to be predominant source of unhydrolyzable lipids in the surface sediments from the Atchafalaya River shelf.
Third and most importantly, resistant clinical strains contain mosaic genes in which sections are replaced by highly altered sequences that differ by approximately 20% at the DNA level, the result of interspecies gene transfer followed by recombination events.
The cards are related to a slightly altered image (first row) and a highly altered one (second row), respectively.
filled with chlorite (cl)., quartz (qtz)., and highly altered pyroxene (pyx). in lower portion of image.
Geothermal systems are commonly hosted in highly altered and fractured rock.
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