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Thus, the heritability of ASDs has been estimated to be ∼90%, making ASDs the most heritable of the childhood onset neuropsychiatric disorders (Sousa et al, 2011).
There's some evidence that disorders tend to run in families, with twin studies suggesting that bipolar disorder is "among the most heritable of medical disorders".
As late as the mid-1970s there was little evidence of a genetic role in autism; now it is thought to be one of the most heritable of all psychiatric conditions.
With a concordance rate as high as 90% based on twin studies [3], ASDs are among the most heritable of neuropsychiatric conditions.
Although ASD is the most heritable of all the psychiatric disorders based upon twin and family studies [28] [31], no single gene or consensus gene combination has been shown to be causally linked to idiopathic autism.
The autism spectrum disorders (ASD) are a complex group of disorders defined by deficits in social interaction, communication and a pattern of circumscribed interests and repetitive behaviours [1] Fundamentally neurobiological in origin, ASD is marked by early developmental onset [2] and is among the most heritable of psychiatric disorders [3], [4].
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RESULTS: PCH1, the most heritable component of cognitive performance, declines with exposure to CMV or HSV-1 regardless of case/relative/control group status (p = 1.09 × 10-5 and 0.01 respectively), with stronger association with exposure to multiple herpes viruses (β = -0.25, p = 7.28 × 10-10).
Refinement of the ADHD phenotype may be possible by concentrating on the most heritable subtypes of ADHD.
ADHD is one of the most heritable psychiatric disorders, with estimates of heritability at approximately 76% [ 2].
The maps of the most heritable traits were mostly comprised of landmarks closely located to each other, indicating patterns of common shape variation in the respective areas.
Despite considerable clinical heterogeneity, SLE is one of the most heritable autoimmune diseases, with a sibling risk ratio of around 30 [ 8].
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