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There are numerous other proteins that travel with eukaryotic replication forks, some of which are known to be involved in checkpoint regulation or nucleosome handling, but most have unknown functions and no bacterial analogue.
Among these unique genes, most have unknown functions.
Because most have unknown effects on the N2 phenotype, we did not and could not correct them all.
We do not know how many metabolites are in the fly, and of those we have measured, most have unknown identities.
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The majority of patients presented with T3 or T4 tumours and most had unknown lymph node involvement before the commencement of CT.
Although most genes have unknown functions, a large collection of data is available describing their transcriptional activities under many different experimental conditions.
We've made it through a large number of mass extinction events, most of which have unknown or only speculatively known causes.
Most of these have unknown function.
Like SCCmec type III of S. aureus 85/2082 and the SCCmec of S. pseudintermedius KM241, the ccr and the mec gene complexes in the WC28 SCCmec were separated by a few genes, most of which have unknown functions, and ψTn554 carrying cadmium resistance determinants (Table S1 and Figure 1).
CYP72A subfamily members are quite diverse, and most of them have unknown functions [ 52].
Most enriched genes have unknown function, and thus should provide a rich source for targeted studies to characterize novel functional categories associated with virulence and protection from virulence.
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