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The most harmful agents were budesonide/formoterol (SUCRA=94%), beclomethasone/formoterol (SUCRA=89%) and fluticasone/salmeterol (SUCRA=78%).
We found that the following were the most harmful agents for being associated with increasing risk of pneumonia: fluticasone/salmeterol, fluticasone/vilanterol and fluticasone according to the SUCRA.
However, our pneumonia sensitivity analysis including studies with a low risk of bias found that the most harmful agents that increased the risk of pneumonia were budesonide/formoterol, beclomethasone/formoterol, and fluticasone/salmeterol.
The following were the most harmful agents because they had a greater risk of pneumonia: fluticasone/salmeterol (SUCRA=89%), fluticasone/vilanterol (SUCRA=88%) and fluticasone (SUCRA=82%; see online supplementary appendix 12).
Evidence on which particles are most harmful would inform effective policies by allowing stricter control of the most harmful agents and could aid understanding of biological pathways, which may differ by constituents or health outcomes.
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The most harmful agent was fluticasone/salmeterol (SUCRA=89%).
Fine particulate matter is, on account of its aerodynamic properties and typical composition (especially diesel particulate matter and carbonaceous particles) the particulate pollutant potentially most harmful to cultural heritage, representing an aesthetic issue and an agent of chemical degradation simultaneously.
2,3,7,8-TCDD (2,3,7,8-tetra 2,3,7,8-tetraodioxin) also known as a major chloroinant in Agent Orange (a herbicidibenzodioxing the Vietnalsoar) [3] is considered to be the most harmful congener.
Alcohol is rated as the most harmful drug.
Among the most harmful are members of the Orobanchaceae.
How can hundreds or even thousands be transported without exposing health care workers to contagious or otherwise harmful agents?
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com