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In microorganisms, most genetic variations involve some important cell function.
However, it is widely perceived that most genetic variations are the result of non-directed processes that are not responsive to specific inducing conditions.
"Most genetic variations do not occur between ethnic groups," he says.
The genotype is the specific allele constitution of an individual SNP that comprises most genetic variations.
We found that in-line with previous publications most genetic variations are found within human populations (Barbujani et al. 1997; Jobling and Gill 2004).
Comparison among K1207, S0108, and FAM18 N. meningitidis genomes at whole genome level and for CDS content demonstrated that most genetic variations occurred in the capsule locus.
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If this is the case, most genetic variation has no impact on fitness — the technical term for how good an organism is at surviving and reproducing.
Kimura's development of the neutral theory was enormously influential, and prompted a flurry of work investigating whether most genetic variation is irrelevant.
Since most genetic variation lies in nonprotein-coding regions of the genome whose presumed function is entirely regulatory, understanding gene regulation in a cell type and developmental state-specific manner will be important to connect human genetic variation to disease mechanisms.
Joint linkage mapping of NAM populations better avoids the confounding effect of population structure, and identified most genetic variation of flowering time (Tables S1 and 1).
Protected area designs may also be optimized to preserve the most genetic variation.
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