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Lack of conservation may limit the application of our approach to most genes, which are less well conserved than heat-shock genes [55], [56].

Most genes which were amplified and upregulated were grouped into 5 genomic regions – 1q, 3q, 8q, 12p and 20q (Table 9).

Most genes which were down regulated throughout degeneration of penicillin production, remained down regulated during sub cultivation.

For most genes, which are not encoded by highly similar gene families, such as dhurrinases, we feel that mutation discovery could be accomplished with lower genomic coverage and therefore lower costs.

Undoubtedly, there is room for debate as to a meaningful definition of essentiality, but it seems that, in general, most genes which are required under rich media conditions will be vital under most other conditions.

A particular complication in bread wheat is that most genes which are present in single copy in the diploid grasses such as rice and purple false brome are represented by three copies.

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Similar(53)

In contrast to most homeobox genes, which contain one or no introns, Meis genes contain 10 or 11 introns in most metazoans.

This pattern, however is biased by the fact that public databases are skewed toward most conserved genes which tend to be genes belonging to the metabolic pathways.

These differences in pathogenic abilities were difficult to relate to gene content since most of genes, which are species-specific and thus potentially involved in species-specific life traits mostly did not have any attributed function.

Gene expression in two organisms or individuals is, until now, compared only for the most similar genes, which is the identical gene in one organism (and two individuals) or the gene pair of closest orthologs in two different organisms.

We performed a genome-wide comparative analysis of functional domains traced in single versus duplicated genes and also focused on the 100 most duplicated genes, which revealed two important aspects.

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