Further gene disruptions and chemical analysis demonstrated that most genes of this ver cluster were essential for verticillin biosynthesis.
This indicated that adaptation of B. platifrons to the deep-sea chemosynthetic environment was mainly mediated by gene family/domain expansion, and the deep-sea mussel has retained most genes of its shallow-water ancestors.
The hunt began last January, at a cost of $10 million a year and with the goal of locating at least 100,000 snips spread out across the genome, which Dr. Collins calculates is the necessary number to tag most genes of possible interest.
Sequence data were lacking for most genes of interest.
For most genes of the DM signature, an increased expression is negatively correlated with patient survival.
Most genes of the SLC26 family encode anion transporters, however, mammalian prestin has only been demonstrated to be an incomplete anion transporter [4] [6].
Specificity is computed as TP/ TP+FP) and is high if most genes of a predicted gene family are found within a known gene family.
Sensitivity is computed as TP/ TP+FN) and is high if most genes of a known gene family are found within a predicted gene family.
We have confirmed the expression of most genes of interest described in this study in human taste buds isolated by LCM, thereby confirming the macaque gene array findings.
The phylogenetic trees show that pAPEC-1-associated virulence genes belong to clusters that include most genes of other ExPEC strains.
The modest regulation of a few genes believed to be involved in the Calvin cycle does not bring greater insight into this question, especially since most genes of the Calvin cycle are also involved in other pathways.
