One way to do this is to postulate a fundamental physical level, whose most accurate computational description identifies the (most fundamental) computation performed by the system.
Estimating the number of genes in human genome has been one of the most fundamental problems in computational biology.
The protein folding problem is therefore one of the most fundamental yet unsolved problems in computational molecular biology.
According to some physicists, the physical world is computational at its most fundamental level.
Protein structural alignment is one of the most fundamental and crucial areas of research in the domain of computational structural biology.
However, integrative analyses have some limitations: the most fundamental challenge is dimensionally, considering that more levels in the analysis increase the computational time and the dimension of unknown parameters [ 396].
And our most fundamental liberties.
That's the most fundamental change.
What are our most fundamental social needs?
The fourth problem is the most fundamental.
