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Some of the most fundamental changes in American tax policy have occurred in wartime.
The most fundamental changes decided were the abolition of parliamentary seats reserved for the military and provisions for the direct election of the president.
It's worth remembering that the most fundamental changes in the relationship between the UK and the EU (and its predecessors) have occurred under Tory PMs.
The most fundamental changes decided at the assembly's two-week session were the abolition of parliamentary seats reserved for the military and provisions for the direct election of the president.
The health care legislation under construction in Congress would force the insurers to conduct business very differently, but the companies had already agreed to some of the most fundamental changes.
This is "one of the most fundamental changes in the history of human warfare," according to PW Singer, a former analyst for the Pentagon and the CIA, in his must-read book, Wired For War: The Robotics Revolution and Defence in the Twenty-First Century.
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That's the most fundamental change.
"I think actually the most fundamental change occurred when I dealt with prostate cancer," he said.
The most fundamental change was embodied in the Nunavut Act, ratified in 1993.
This is the most fundamental change necessary to achieving gender equity in the current and future workplace.
But it was the introduction of management that was the most fundamental change of the Thatcher era.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com