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Since protein functions are inter-correlated and most functional labels often have a relatively small number of member proteins, these algorithms ignore the interrelationship among labels, which can often be used to boost the prediction accuracy [ 3, 19].
In fact, most functional labels are only annotated with a rather small number of proteins.
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One of the most well-studied problems in computational network biology is the prediction of protein functional labels from distance and neighborhood structure in the protein protein interaction network (PPI network).
That's an eternity for most functional offenses.
Even Thomé's most functional furniture and objects entertain with bold patterns and color.
"I only can say that I will be most functional in China," he said finally.
He thinks Medicare is the most functional part of the health-care system.
By 1960, weather vanes, once the most functional of ornaments, had become art.
Typically each state carries one of two functional labels: open or closed.
We're still the most functional democracy in the world.
In most functional medicine circles, you want this number to be above 400.
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