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Nummular headache, most frequently localized in the parietal region, seems to be associated with local increase of pain sensitivity to mechanical stimulation and trophic changes inside the painful area [3].
26 Lymphangioleiomyomas consist of chyle-filled lymphatic masses of varying sizes that are most frequently localized to the retroperitoneum, pelvis, and posterior mediastinum.
They are most frequently localized in the skin, but 5% of all melanomas interest also extracutaneous sites as mucosal surfaces, parenchymatous organs, the retroperitoneum area, and the ocular ball.
For instance, human Crohn's disease (CD) is most frequently localized in the terminal ileum [ 7], and it also becomes increasingly evident that human ulcerative colitis (UC) might also involve the terminal ileum due to further extension of the inflammatory process either by backwash from the colon or by other factors [ 8, 9].
Previous studies have most frequently localized foam-like MGCs in lesions containing cholesterol and lipid deposits, such as xanthomas or xanthogranulomas [ 48], and these MGCs might develop when a cell fusion stimulus is also accompanied by a factor stimulating lipid uptake [ 49].
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Generally, central neurocytoma affects young adults with the tumors most frequently localizing in the supratentorial ventricular system and demonstrating calcification on computed tomography (CT) images [ 3, 4] although various cases of extraventricular neurocytoma have also been reported [ 5– 9].
The rhinocerebral presentation is the most frequently reported localized symptom followed by pulmonary, cutaneous, cerebral, gastrointestinal, and disseminated infections (3, 8 ).
Speckles and Cajal bodies frequently localized in direct neighborhood to vimentin bundles.
In hepatocytes, the agglomerated nanoceria frequently localized to the plasma membrane facing bile canaliculi.
The most significant associations between variations in methylation and gene expression were observed in the upstream region from the TSS, which is not surprising since the CpG sites are frequently localized within gene promoters.
The separated plasmids were frequently localized on the sister chromosomes symmetrically at the end of mitosis.
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