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Drugs most frequently implicated are aromatic antiepileptic agents, sulfonamides and allopurinol.
Although the exact cause has yet to be defined, the intervertebral disk and its age-related changes have been most frequently implicated.
The functionalized textile material cumulate the anti-adherent properties of magnetite and microbicidal activity of eugenol and limonene, exhibiting significant anti-adherence and anti-biofilm properties against two of the bacterial pathogens most frequently implicated in the etiology of cutaneous wound infections.
Most important in the pathogenesis of infection is the colonization of the device surface and the consecutive formation of a biofilm (Zimmerli and Moser 2012; Gosheger et al. 2004), in which Staphylococcus aureus and koagulase-negative Staphylococci are most frequently implicated as the etiologic agents (Zimmerli and Ochsner 2003; Hunter and Dandy 1977).
The most frequently implicated drugs were opioid analgesics, diuretics, systemic corticosteroids, anticoagulants and antibiotics.
Overexpression of the human c-MYC (MYC) oncogene is one of the most frequently implicated events in the pathogenesis of hepatocellular carcinoma (HCC).
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Dimerization of HER3 with HER2 is known to be one of the most mitogenic protein complexes [24] and is frequently implicated as a potential drug resistance mechanism [25], [26].
Protein kinases are critical regulators for most cellular processes and misregulation of their activity is frequently implicated in disease development.
Alterations in lung mechanics and reduction in pulmonary compliance are frequently implicated in postsurgical cardiac patients [ 59], and most patients remain sedated and nursed in a supine position before being weaned from the ventilator.
In addition to these mechanisms, selfish elements have been frequently implicated in the translocation of genomic DNA, for example in most plants [ 52] and in trypanosomes [ 53].
The most common causative organism is S. aureus with Streptococcus pneumonia and Haemophilus influenzae less frequently implicated [ 4].
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com