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(1) The most frequent varieties are those that possess inactive mtDNA products of mitochondrial genome rearrangements, including partial deletions and amplifications of remaining fragments (rho− mutants).
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At the same time, pain is one of the most frequent symptoms of a variety of pathological disorders and represents a major clinical challenge.
Two principal patterns are known: the cavernous variety (the most frequent) and capillary haemangioma.
Notably, loss of 8p is one of the most frequent chromosomal alterations in a variety of cancers including HCC [ 11– 16].
PVT-1, which encodes a long noncoding RNA, mapped to chromosome 8q24 whose copy-number amplification is one of the most frequent events in a wide variety of malignant diseases.
Mutations of the p53 tumor suppressor gene which encodes a protein involved in the growth and regulation of cells and of components of the DNA damage control response is one of the most frequent genetic alteration in a variety of malignancies.
Amplification of 8q24 is one of the most frequent events in a wide variety of malignant diseases including CRC, and has been associated with reduced survival duration in several studies (Popescu and Zimonjic, 2002; Lancaster et al, 2004; Guan et al, 2007).
In the practice of emergency and acute care medicine, pain is the most frequent symptom in patients with a wide variety of injuries and illness.
Gliomas are the most frequent primary brain tumors and include a variety of different histological tumor types and malignancy grades.
A systematic review of 123 articles about authorship issues revealed a wide variety of problems, the most frequent being authorship perceptions, definitions and practices [ 1].
Sites were hosted by a variety of organizations, the most frequent being online media, such as WebMD or healthcare organizations such as cancer centers, public hospitals, and private practices.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com