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Visualization of large molecular data sets using the Molecule Cloud approach allows scientists to get information about the composition of molecular databases and their most frequent structural features easily.
The most frequent structural abnormality, t(12 21), was more common among non-Hispanics than Hispanics.
Translocations and deletions involving a breakpoint at 1p11-p22 were the most frequent structural aberrations.
Translocations of chromosomal band 2p21 are the second most frequent structural chromosomal rearrangement, representing a particular cytogenetic subgroup [ 2].
At the cytogenetic level, the most frequent structural rearrangements in papillary cancers are abnormalities with breakpoints at 10q11.2 (Roque et al, 2001).
The (virtual) consensus structure is calculated by determining, for each position along the chain, the most frequent structural state found within the population, i.e. unpaired ".", paired upstream "(" or paired downstream ")".
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Ectopic thyroid and agenesis are the most frequent thyroid structural malformations.
The most frequent facultative structural aberrations were gains of 1q and loss of 16q that were present in 21% each.
The most frequent type of structural change in all investigated angiosperm nuclear genomes has been observed to be the differential insertion and subsequent instability of transposable elements (TEs).
A similar analysis of CNVs in family 2 has identified a 109 kb gain at 19q13.41 that is specific to the schizophrenia patient in family 2. Translocations involving 19q13 are a frequent finding in follicular adenomas of the thyroid and may represent the most frequent type of structural aberration in human epithelial tumors [23].
Using multivariate regression analysis, the circadian MOPP fluctuation was the most frequent predictor for advanced structural and functional glaucomatous damage [ 83].
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