Skipped exon was the most frequent splicing alteration in CLL specimens with 128 significant events (P-value <0.05, minimum inclusion level difference >0.1).
The top cluster, centered around the most frequent sequence type S14, contained specimens from the Northern GBR, the Coral Sea, Guam, Taiwan, Papua New Guinea, and Sulawesi (shaded in blue).
The bottom cluster, centered around the second most frequent sequence type S10, contained specimens from the Central and Southern GBR, the Coral Sea, and PNG (shaded in dark green).
HPV16, 51, 33 and 31 are amongst the five most frequent genotypes found in HSIL specimens in previous studies from Spain and France [ 7, 36].
The most frequent HPV genotypes found in all specimens were HPV16 (26.0%), 31 (10.7%) and 58 (8.0%).
Respiratory specimens constituted the most frequent source of A. baumannii (56.3%) and P. aeruginosa (43.6%); urine samples were the most frequent source of K. pneumoniae (28.8%).
This genotype was also the most frequent ESBL genotype in rectal swab specimens (n = 22, 45.8%) and the second most common in blood cultures (n = 5, 20.8%).
While in medical wards urine continued to be the first site of isolation, in the surgical wards pus/wound specimens were the most frequent sites of infection (23, 24).
Specimens carrying the most frequent haplotypes (named F5-2, C5-1, F10-1, C10-3) have been selected as parental individuals in a backcross for SNP-based LD and genetic mapping of this region.
Examples of specimen images with the most frequent staining patterns are shown in Figure 1. Figure 1 Typical HEp-2 cells with different staining patterns.
