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While there were elevated positive moods and enjoyment for trips with driver-preferred music, this background also produced the most frequent severe driver miscalculations and inaccuracies, violations, and aggressive driving.
This OR increased to 43.5 (95% CI, 18.3 103.5) for EAC in those with the most frequent, severe, and long-standing symptoms.32 The widely disseminated information from this study and others33, 34, 35 suggest a strong and probably causal relationship between gastroesophageal reflux symptoms and EAC.
Anterior cruciate ligament (ACL) injuries are among the most frequent severe knee injuries affecting physically active children and adolescents.
Based on CE interview data, the most frequent, severe, and impactful symptoms were "fatigue", "shoulder pain", and "lower back pain", respectively.
The most frequent severe comorbidities were hypertension (57.3%), diabetes mellitus (16.1%) and peptic ulcer (12.7%).
Associated side effects are reported in Table 4. Haematological toxicity was the most frequent severe toxicity.
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Indeed, hemorrhaging represents the most-frequent severe adverse event in patients receiving extracorporeal circulatory or respiratory support, with reported rates up to 30% [ 2, 4].
Also, Nekrasova et al (2005) found that, the reduction in BMD most frequent and severe in patients with severe thyrotoxicosis but this loss of BMD does not depend on disease duration [ 31].
Table 4 Comparison of methods according to the most severe, frequent, and bothersome AS symptoms Most Frequent Most Severe Most Impactful How was this Identified?
Infections, particularly bacterial infections, are one of the most frequent and severe complications of advanced ALDs, such as alcoholic cirrhosis and severe alcoholic hepatitis (sAH).
Medical File Review was used to assess occurrence of pain episodes and acute chest syndrome (among the most frequent and severe complications of SCD) to determine disease severity using a weighted score as outlined by Day [ 30].
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