The most frequent serious safety issues were surgery complications or damages related to invasive procedures, three of them related to the handling of breathing devices and two of them with reaction after blood transfusions.
9 22 Most studies included frequent safety assessments of laboratory data; only two studies, however, reported predefined safety outcomes.
We need to improve our understanding of the reasons why GPs in out-of-hours healthcare make errors in clinical reasoning, as these are the most frequent causes of patient safety incidents.
The most frequent topics were overall efficacy and safety strategy.
Furthermore, healthcare-associated infections (HCAIs) are known to be the most frequent adverse event that threatens patient safety; as cited in the literature and within our study.
Discontinuation due to ineffectiveness seemed to be quite constant over time, resulting in a linear Kaplan-Meier curve, whereas discontinuation due to safety issues was most frequent during the first two years of therapy.
In general, women firefighters report similar job stressors to men with the most frequent being sleep disturbance, wage/benefit concerns, safety concerns, equipment concerns, and job skills concerns (61).
Using location specific collision data (e.g., collision frequency per collision configuration for a target location), safety engineers identify (the most) frequent collision configurations.
Finally, discontinuation due to elective reasons not directly related to product safety or ineffectiveness was most frequent around year four, when a new subcutaneous TNF blocker (adalimumab) became available in Belgium.
With regard to the safety of IA chemotherapy, the most frequent adverse event was anorexia.
