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Dr. Robert Katzman, the neurologist, researcher and medical activist who redefined Alzheimer's disease as a major public health problem and as the most frequent progressive form of dementia in aging, died Sept. 16 at his home in San Diego.
Ataxia, dysarthria, spasticity with extensor plantar reflexes, distal muscle wasting, sensorimotor neuropathy and horizontal gaze-evoked nystagmus constitute the most frequent progressive neurological signs.
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Sporadic inclusion body myositis (sIBM) is the most frequent acquired progressive myopathy presenting over 50 years of age in Western populations [ 13], albeit rare.
One of the most frequent complaints from progressive groups during the Obama era is that the White House has taken too long to finalize key regulations on everything from energy-efficiency standards to mine safety.
The most frequent clinical presentation is progressive myelopathy.
In a retrospective study in 11 dogs, the most frequent clinical finding was progressive abdominal enlargement caused by a hepatic mass [ 16].
By the data cut‐off, 16 patients (84.2%) had terminated treatment with trial medication, with the most frequent reason for discontinuation being progressive disease (nine patients, 47.4%).
ANCA-associated systemic vasculitis (AAV) has a prevalence of 14 30 patients per 100,000 [ 1] and its most frequent severe manifestations include rapidly progressive glomerulonephritis leading to dialysis-requiring renal failure and alveolar capillaritis leading to pulmonary haemorrhage.
T cells dominated by the CD3+ subtype reported in the pericystic adventitia of the hepatic cysts in sheep, while CD8+ and CD4+ cells were the most frequent populations in cattle with progressive and regressive cysts, respectively [ 29, 37].
The auditory feature of DFNA5 closely resembles that of the most frequent type of ARHI, namely, sensorineural progressive loss that begins in the high frequencies.
Chronic bronchitis, asthma, bronchiectasis and pulmonary fibrosis account for the most frequent long-term respiratory sequelae, with progressive decline occurring over many years [ 2- 5].
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