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The most frequent ocular symptoms are: retro-orbital headache, diplopia, photopsia, blurred vision, and photophobia.
Loss of vision and ocular motility deficit are the most frequent ocular symptoms reported.
The most frequent ocular injection-related adverse event was conjunctival haemorrhage (table 2).
Blepharitis is one of the most frequent ocular pathologies, and involves inflammation of the palpebral margin.
Ocular symptoms were first reported by Katz, being diplopia and vision loss the most frequent ocular complaints [ 1, 5].
The most frequent ocular AE in each group was conjunctival hyperaemia, which was usually mild in severity.
Similar(41)
Most frequent overall ocular events of particular interest were retinal pigment epithelial tears (27 patients; <1%) and intraocular pressure-related events (12 patients; <0.3%).
Most frequent non-ocular event of particular interest was stroke (19 patients; 0.4%); annual incidence of stroke was low across all registries (0.0 0.5%).
The most frequent non-ocular events were non-cardiac arterial thrombotic events, notably stroke (recorded as cerebral haemorrhage, cerebral infarction, cerebrovascular accident or intracranial haemorrhage; 19 patients, 0.43%) (table 3).
Most frequent anterior segment ocular findings in our study cohort were episcleritis in eight out of 50 patients (16%), iris nodules in nine out of 50 patients (18%), and cataract in 19 out of 50 patients (38%); three out of the nine patients with iris nodules had cells in the anterior chamber.
The most frequent cause of ocular trauma in women was home related work (52.2%), followed by the outdoor activities related injuries (30.4%).
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