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Obstructive jaundice and/or abdominal/back pain were the most common pre-operative symptoms and elevated values of pancreatic enzymes and cholestasis parameters were the most frequent laboratory abnormalities.
The most frequent laboratory finding was mild to moderate hypoalbuminaemia with concurrent hyperproteinemia, as was the case in the dog described herein [ 16].
The most frequent laboratory hepatic abnormalities observed in patients on long-term PN are elevations in serum levels of lactate dehydrogenase, alkaline phosphatase, and total bilirubin.
Concurrently with these findings the data safety profile of this treatment should be considered, since 18.5% of the reasons for prematurely discontinuation of treatment were due to adverse events, being the most frequent laboratory abnormalities (40%) and death (20%).
The most frequent laboratory abnormality was high level of serum triglycerides 10/11 cases, 5 cases associated high levels of serum total cholesterol with 4 high low-density lipoprotein cholesterol (LDL-c) and 9 cases had low high-density lipoprotein cholesterol (HDL-c).
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Shock was the most common clinical criteria, while the presence of thrombocytopenia was the most frequent of the laboratory criteria.
The most frequent biochemical nonhematologic laboratory AEs (any grade) associated with bosutinib were elevations in alanine aminotransferase (ALT; 33% vs. 9%; P < 0.001) and aspartate aminotransferase (AST; 28% vs. 10%; P < 0.001) as compared with imatinib.
The most frequent of these were laboratory abnormalities (see next section) and influenza-like syndromes.
Finally, we also analysed T109G, the second most frequent mutation in the laboratory strains, which was also identified in a clinical isolate (Table 3, Figure 1).
In this article, we present this standardized method of evaluation and classification of histological features and demonstrate the most frequent associations among histological findings, laboratory data, clinical phenotype, and injury severity at presentation.
The 16S rRNA gene is the most frequent target used in clinical laboratories for molecular identification, but in some cases this tool can only help to identify the genus and it is not discriminative enough for speciation within the genus.
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