Introduction Infection is the most frequent extra-corporeal membrane oxygenation adverse event.
Neuroblastic tumors account for 9 10% of pediatric tumors and neuroblastoma (NB) is the most frequent extra-cranial solid tumor and the first cause of death in pre-school age children [1].
Liver involvement is the most frequent extra-renal manifestation in ADPKD [ 1– 3].
The most frequent extra-abdominal metastatic site in cases of ovarian carcinoma is the pleural cavity [ 32, 33].
The most frequent extra-cutaneous diseases associated with psoriasis were depression (15.4%), hypertension (13.3%), obesity (8.9%) and type 2 DM (7.3%).
Neuroblastoma (NB) is the most frequent extra-cranial solid tumour in children, originating from immature neural crest cells of the sympathetic nervous system [ 1].
Although the most frequent extra-pulmonary manifestations of respiratory syncytial virus (RSV) infection involve the cardiovascular system, no data regarding heart function in infants with bronchiolitis associated with RSV infection have yet been systematically collected.
The most frequent extra-pulmonary manifestations of respiratory syncytial virus (RSV) infection involve the cardiovascular system [ 1], and include cardiovascolar failure with hypotension and inotrope requirement, associated with myocardial damage, cardiac arrhythmias and pericardial tamponade, particularly in patients admitted to pediatric intensive care units (PICUs) [ 2- 9].
The most frequent single extra abnormalities to del 5q) were: del(12p), trisomy 21, trisomy 8, del(20q) [ 2], and the recently identified del(15)(q26.1), and del(3)(q26.1), respectively deleting the CHD2, and THPO genes [ 3].
