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The most frequent differences between isoforms resided in mutual exchanges of glutamic (E) and aspartic (D) acid residues (more than 20%% of all substitutions; Fig. 3).
The position with the most frequent differences between isoforms (T46 in spinach PsbO) is located in G1 domain, the position with the second most frequent differences between isoforms (E139 in spinach PsbO) is in G4 domain (see positions 47 and 140 in alignment in Additional file 2).
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There was a trend among all sites toward higher methylation in the adult samples with the most frequent difference in beta being 0.1.
Differences between families are the most frequent class of differences among PsbO sequences (Additional files 2 and 5).
The most frequent cause for differences in identification of diagnostic reasoning strategy was examinees' use of more than one strategy.
The authors found that GALR1 methylation is among the most frequent and consistent methylation differences between benign and cancerous endometrium.
Selecting the 20 most associated diagnostic codes generally outperformed models based on the 20 most frequent codes, but the differences decreased with increasing code aggregation.
Different ploid level is one of the most frequent reasons leading to difference in chromosome numbers in some genera of Asteraceae (Dematteis and Fernandez 2000; Keil et al. 1988; Solbrig et al. 1972).
Y181C and T215Y were the most frequent mutations associated with interpretation differences.
Among the significant outcome differences, the most frequent cardiac complication was atrial fibrillation, the most frequent respiratory complication was acute respiratory failure, the most frequent infectious complication was pneumonia followed by sepsis, and the most frequent new organ failure was acute renal failure, followed by congestive heart failure.
11 14 15 Musculoskeletal involvement, including joints, tendons and muscles, is the most frequent clinical feature, highlighting the difference to other SSc forms.
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