Exact(3)
Facial erythematous eruptions is the most frequent cutaneous adverse manifestation associated with sorafenib, its overall incidence is 63% [ 15].
Hand-foot skin reaction (HFSR) is the 2nd most frequent cutaneous adverse manifestation associated with sorafenib, its overall incidence is 30% to 60% [ 10, 15- 17].
It is one of the most frequent cutaneous diseases, affecting more than 80% of the population at some point in their lives.
Similar(57)
Although prostate cancer (PrCa) is the most frequent non-cutaneous cancer among men in America and the UK, very little is known regarding the underlying aetiology [ 1– 3].
The most frequent extra-cutaneous diseases associated with psoriasis were depression (15.4%), hypertension (13.3%), obesity (8.9%) and type 2 DM (7.3%).
Beta-lactam antibiotics were found to be the most frequent cause of adverse cutaneous drug reactions (42.7%), followed by non-steroidal anti-inflammatory drugs (16.5%).
Fever, malaise, ostealgia, weight loss, and anemia were the most frequent symptoms, followed by cutaneous lesions, lymphadenopathy, hepatosplenomegaly, cough, sputum, and stethalgia.
This formulation has significant advantages in terms of tolerability compared to conventional doxorubicin: the most frequent toxicities consist of cutaneous and mucosal toxicity (hand-foot syndrome and stomatitis), with a very low rate of nausea, hair loss, extravasation-related necrosis or reduction in the ventricular ejection fraction [ 15- 17].
Cutaneous attacks are most frequent in occurrence, followed by abdominal attacks, which are known to be extremely painful and laryngeal attacks, which can be fatal if untreated [ 1, 4, 6].
Cutaneous manifestations are the most frequent.
The localized cutaneous leishmaniasis (CL) is most frequent and patients can present spontaneous clinical cure.
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