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Based on clinical studies with [68Ga]NOTA-c RGDyK) (Jeong et al. 2008; Kim et al. 2012) and the dimers [68Ga]NOTA-c RGDyKF]FPPRGD2 (Chen et al. 2004a; Zhang et al. 2006; Wu et al. 2007a; Choyke 2011; Mittra et al. 2011; Liu et al. 2010), it seems that the most favourable conformations are the monomeric and dimeric scaffolds.
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In the piperazine compounds, the phenyl ring preferentially adopts a perpendicular orientation, whereas an almost planar orientation seems to be the most favourable conformation for the tetrahydropyridine compounds.
Among which the best and the most three energetically favourable conformations with fairly similar GOLD fitness score of each ligand was selected.
In case of GlcNAc(4S) and GlcNAc 6S), the strong interaction between sulfate groups and hydrogens of the hydroxyl groups defines the most favourable ω dihedral angle conformation.
One conformation with an intramolecular H-bond was found which was energetically the most favorable conformation.
In order to generate recombinant proteins with natural conformation, it is most favourable to use expression hosts of the same biological kingdom, since they likely produce the same post-translational modifications and recognise the same signals for synthesis, processing, and secretion as the organism, which the sequence was originally derived from.
The layer shape similar to the glenoid cartilage shows the most favourable mechanical effects.
State-approved foundations benefit from the most favourable tax regime.
It's the most favourable definition of me.
The bank offering the most favourable terms wins.The financial environment has been a challenge for MaxBips.
Australia's ratio of export to import prices is the most favourable in 140 years.
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