In embryoid bodies in which the two constituent cell types had the most extreme difference in binding affinity, the highly adhesive wildtype ES cells when differentiated, nevertheless, enveloped the weakly adhesive E-cadherin null ES cells (Fig. 5B,C).
BCL6 is the most extreme example of this mixed binding phenomenon.
One of the most extreme outliers within the hypermethylated set was for increased human binding strength of a MeCP2 (motif_02) motif.
The most extreme case is gene locus Medtr8g070990 that encodes a putative RNA-binding protein and has 31 isoforms.
As the most extreme example of this apparent incongruence, the most prominent peak found in the in vitro binding profile for the closed and open complexes coincides with the λPBL promoter.
In the most extreme examples the SPTPPPVPRRGTHT, QPPVPSLPPRNIKP, KKPPPPVPKKPAKS, RRPPVPPR, and RRAPPPVPKKPAKG ligands each have five of the 10 different SH3 binding consensus sequences.
Alabama's law is the most extreme.
The most extreme cases include fatal overdoses.
Mr Gephardt is the most extreme example.
Its most extreme feature is its head.
