One point about RNA that has really not penetrated the consciousness of most biologists yet is that it is extensively edited, and by editing I mean deamination of adenosines to form inosines, and cytosines to form uracil, which changes the sequence and structure of the RNA.
TbRGG2 knockdowns lead to a dramatic decrease of extensively edited RNAs and moderate stabilization of never-edited and minimally edited RNAs [32].
Extensively edited genes were more divergent among the genera than non-edited and rRNA genes.
But unlike those on the Web site, the papers given to the Security Council had been extensively edited, to remove sensitive information on unconventional arms.
As elaborate applications with carefully pruned CVs and extensively edited covering letters disappear into an abyss you begin to wonder what you're doing wrong.
In the remaining songs, the lyrics have been extensively edited -- up to 60 times in a single song -- to eliminate references to drugs, violence, profanity and hate.
Like A6, the two selected regions of the ND7 mRNA are constitutively and extensively edited.
So why do the extensively edited trypanosome mitochondrial genes contain multiple ORFs although their mRNAs do not contain complete coding information until edited?
Precursor-mRNAs are often extensively edited by specific uridine insertion or deletion that is directed by small guide RNAs (gRNAs).
