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Their occurrence has been most extensively characterised at the telomeric ends of eukaryotic chromosomes, whose DNA comprises such sequences, and where the extreme 3′ ends are single-stranded.
Of this family, src is most extensively characterised.
The most extensively characterised MCT isoform is MCT1, which is expressed in most tissues.
Of the five Plks identified in humans to date, polo-like kinase 1 (Plk1) is the most extensively characterised.
Expression of the leftmost adenoviral gene, termed early region 1A (E1A) is crucial for transformation and has been most extensively characterised in HAdV-5.
Although most extensively characterised for their roles in development, Eph receptors and ephrin ligands are re-expressed in a variety of diseases including a number of human malignancies (Pasquale, 2010).
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The DRB region exhibits the most elaborate polymorphisms in MHC class II genes, and these have been extensively characterised in primates, due to their importance in immunological research [ 23- 31].
These tumours, which have been extensively characterised, represent the heterogeneity of the disease and retain the most important genetic features of the originator tumour (Rubio-Viqueira et al, 2006; Rubio-Viqueira and Hidalgo, 2009).
In this paper, we use CORM-3 for most respiration measurements, since this is a water-soluble CO-RM that has been extensively characterised by others and ourselves (for references, see Introduction).
The gypsum used in the experiments was extensively characterised using TGA, DSC, MIP, and NMR.
Moreover, the nanohybrid systems were extensively characterised, and the strong influence of pH on the formation of the semiconductor nanocrystals and their fluorescent response was verified.
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