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The most extensive experimental data are concentration measurements in 20 vertical profiles at a few depths and times.
Even the most extensive experimental study can only explore a small sub-set of all possible combinations found in vivo.
To date, the most extensive experimental assessment of druggability on various targets has been performed by Hajduk and coworkers [27].
Research on Drosophila genetics has provided the most extensive experimental evidence for sexually antagonistic genes through such selective breeding, in the laboratory environment (e.g., Rice 1992; Chippindale et al. 2001), as well as via studies of drift in small populations (Hesketh et al. 2013).
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Thus, even in E. coli, the species in which the most extensive computational and experimental screens for sRNAs have been conducted to date, it is likely that only a subset of regulatory RNAs have been identified.
This model was preferred over alternative models because it is based on the most extensive set of experimental data.
Previously, the most extensive comparison of experimental and theoretical salt dependence for an RNA−protein interaction involved fragments of the phage λ N protein and its cognate RNA.
I-Mutant 2.0 generates results based on ProTherm database which contains the most extensive amount of thermodynamic experimental data on free energy alterations of proteins stability owing to mutations.
The most extensive measurements have been done with an experimental steel chimney of 28 m height and 0.91 m diameter, which has been erected on the test field of the Technical University Aachen, Germany.
Human health in the built environment is one of the most critically needed research efforts, requiring both extensive experimental and field research.
Essential gene predictions for the enterobacterial ancestral core were compared to extensive experimental data and revealed the most promising new targets for future development of control strategies such as new broad-spectrum antibiotics to treat disease caused by enterobacteria.
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