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The pharmacological results showed that some of the compounds displayed moderate to high levels of antitumor activities against the tested cancer cell lines and that most exhibited more potent inhibitory activities compared with ursolic acid.
It took another month or so of back-and-forth emails and phone calls with Stetson to assure him that the piece would be flattering and truthful because those were the two qualities most exhibited by him and his answers to Bill Bryson's (the Gainesville guy, not the travel-writer guy) questions.
Mice that ran the least displayed the lowest levels of Myog whereas mice that ran the most exhibited the highest levels of Myog.
All five of the PEGylated variants were found to possess catalytic efficiencies (Vmax/Km) exceeding that of the corresponding WT-his construct, although most exhibited a decrease of 2-fold or less in Vmax (Table 1).
In cells with high Sema3E/Plexin-D1 activity such as P0-3E-1 cexhibitedt exhibited predominant nuclear localization of Snail1 (64% ±8%[mean ± standard deviation of three experiments]), whereas most cells with low Sema3E/Plexin-D1 activity displayed a predominantly cytosolic distribution of Snail1 (for example: P0, 78% ±6%cytosolic Snail1 localization) (Fig. 5D).
Most exhibited levels similar to that induced by Brefeldin A (BFA) treatment, which redistributes Golgi proteins to the ER (Fujiwara et al., 1988).
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Numerous crystal structures have been determined, and most exhibit conserved three-dimensional architectures.
Most exhibit antibacterial and antifungal role.
Nevertheless, the distinctions between these disorders are somewhat blurred and most exhibit significant clinical and molecular heterogeneity.
These populations do not exhibit growth senescence upon serial passage, and most exhibit an increased predilection for developing stochastic mammary tumors.
A generalized linear model revealed 92.4% of the paralog pairs exhibited expression divergence, with most exhibiting significant gene and tissue interactions indicating complementary expression patterns in different tissues.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com