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Most exacerbations remained unreported to the healthcare professional.
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The mechanisms of virus-induced exacerbations remain unclear, however.
Although timely treatment of COPD exacerbations seems clinically important, nearly half of these exacerbations remain unreported and subsequently untreated.
Our study indicates that a substantial amount of exacerbations remain partly or completely unmanaged.
Exacerbations remain difficult events to detect as there is currently no diagnostic biomarker [ 5].
Mechanisms underlying the development of virus-induced asthma exacerbations remain unclear.
The mechanisms of these virus-induced asthmatic exacerbations remain poorly understood.
Several studies have shown that almost 50% of exacerbations remain unreported and subsequently do not receive adequate treatment [ 8- 10].
39% of subjects recovering from viral exacerbation remained positive to virological testing at follow-up despite improvement in clinical symptoms.
Although most exacerbations are treated in the community [ 5], exacerbations are the main cause for hospitalisations in COPD patients [ 5, 6].
NIV in acute respiratory failure (ARF) due to bronchiectasis exacerbation remain less recommended.
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