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This system has the most evidence regarding improvement of outcome in patients undergoing high-risk surgery and therefore should be strongly considered in such a setting [ 37- 41].
Most evidence regarding the reduction in morbidity and mortality associated with perindopril has been obtained from the large EUROPA, PROGRESS, and ASCOT-BPLA studies which considered patient-oriented outcomes in parallel with changes to blood pressure.
Although most evidence regarding the role of ultrasonographic assessment of diaphragm thickening relates to studies performed on spontaneously breathing patients [ 13, 17- 19], it was recently demonstrated how this index might be useful for the assessment of the effort of breathing during non-invasive PSV [ 33].
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IARC recognizes that where solid human/epidemiologic data are available, such data provide the most relevant evidence regarding carcinogenicity.
As the New America incident reveals, the most relevant evidence regarding these relationships was likely in the hands of Google and its proposed beneficiaries: If Mr. Lynn hadn't spilled to the New York Times, the emails evidencing New America's concern about losing Google's funding wouldn't have come to light.
The most definite evidence regarding the extent of interest in classical learning is to be found in catalogues of names and in lists of classical quotations and translations, but there is another kind of evidence, which is contained in the lives of the earliest native bishops of Iceland (cf. Biskupa Sögur, Copenhagen, 1858).
EBM underpins that information provided from randomized trials, and systematic reviews of randomized trials represent the most reliable evidence regarding intervention effects [ 3, 4].
The DCCT/EDIC study provides the most convincing evidence regarding glycemic control and risk of CVD in type 1 diabetes (7).
17 A trial randomising patients to different waiting periods after surgery would provide the most definitive evidence regarding the effect of the interval from surgery to radiotherapy on local recurrence in breast cancer but would be unethical.
Most available evidence regarding the effects of PEEP from animal studies has been extrapolated to humans based on the assumption that the effects of mechanical ventilation on humans and animals are similar.
As a safety measure, the Japanese PMD ACT requires MAHs to provide the most recent evidence regarding the effectiveness and safety profile in the package inserts of drugs, medical devices, and regenerative products (Brief overview of the Draft Amendment of Pharmaceutical Affairs Law (PAL)).
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com