Sentence examples for most enriched set from inspiring English sources

GSEA analysis against the gene sets in Biocarta database yielded β -oxidation pathway as the most enriched set in HCRs (FDR q<0.001) and STAT3 pathway as the most enriched set in LCRs (FDR q=0.033).

Interestingly, out of all the secretomes we have explored, the AVI secretome exhibited the most enriched set of CAZymes (over 90% of the total number of identified peptides).

The gene lists in the next most enriched set, Development and Differentiation, similarly show large overlap due again to the presence of the signalling pathway genes mentioned above, and also transcription factors Foxc2, Foxo3, Lmx1a, Lmx1b.

The 2 most enriched sets in LCR gastrocnemius muscle (FDR q≤0.001) spanned genes expressed in renal cell carcinoma and chronic myeloid leukemia (Supplemental Table S6), both sets including genes of various signaling pathways (e.g., MAPK signaling route).

Perhaps most interesting, however, the ninth most enriched gene set to be repressed by SRA overexpression in ST2 cells was NEMETH_TNF_UP (Q

We selected the top-three gene sets per spot in each tissue and merged them into one global list of most enriched gene sets in all spots.

Differentially expressed probes were also subjected to Metacore Pathway analysis (Thomson Reuters, London, UK) to identify enrichment of pathways and processes, using hyper-geometric distributions to determine the most enriched gene sets (FDR q<0.05).

Most enriched gene sets included biological processes such as oxido-reductase activity; valine, leucine,and isoleucine degradation; fatty acid β -oxidation; carboxylic acid metabolic processes; as well as cellular compartments like mitochondrion and ribosome.

We observed that the broadest terms, genetic disorder and cancer, were the most enriched for the set of all differentially expressed genes.

As expected, it identified the ATCRAT consensus as the most enriched motif in the set of sequences, by a vast margin (Table  11, entry 1).

Strikingly, we found that a GATA motif corresponded to five of the top eight most enriched motifs in the set of K562-unique peaks that did not have a Kaiso motif; the other 3 motifs corresponded to reported motifs for CTCF or CTCFL.