Showing where the greatest changes are likely to occur will allow surveillance to be most efficiently targeted.
The desired behaviour could be most efficiently targeted in this manner, supporting some intriguing speculations about nonlinear mechanisms in biological signaling.
Especially transcription factor E2F1 was among the most efficiently targeted pro-proliferative proteins identified for the three microRNAs despite transcription factors from the E2F family being major governors of G1/S transition.
For AEM to most efficiently target, implement and monitor, they require comparable evaluation of results, describing their quantitative effects on biodiversity and nature conservation.
In addition, there is a growing interest in tailoring HIV treatment guidelines to most efficiently target programmes [ 10, 11].
While GCRS was devised as a global assessment, doctors may be interested in knowing their performance in particular domains in order to most efficiently target training.
For the 79 million individuals in the U.S. with the broader spectrum of prediabetes, reliable and straightforward means for distinguishing those who will progress to diabetes from those who will not are needed to most efficiently target resources.
Future research should focus on the effectiveness and costs of prevention and intervention programmes for childhood sleep problems, and delineating to which populations these can most efficiently be targeted.
The notable success of Cas9-based genome engineering in many different species, including studies that targeted every gene in the genome (Shalem et al., 2014; Wang et al., 2014), demonstrates that most sequences can be efficiently targeted independent of species and cell type.
Thus, Mcl-1, which is efficiently targeted by wogonin, may be the most relevant therapeutic target in multiple types of cancer.
Importantly, most of the α-amylase activity was detected in the culture medium, confirming that the protein was efficiently targeted to the secretory pathway of the yeast cells (Fig. 1), which greatly facilitated the subsequent purification step.
