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This shows that the most efficiently recognized citrullinated peptides correspond to three regions of human fibrinogen.
The citrullinated epitopes of human fibrinogen most efficiently recognized by RA autoantibodies are confined to three regions of its polypeptides.
However, previously published observations [ 3, 4] demonstrated that this AUG is actually the most efficiently recognized by the translation machinery in the EMCV IRES.
One of the most efficiently recognized lesions is 1, N-ethenoadenine (εA), which is formed under conditions of lipid peroxidation or upon exposure to vinyl chlorides.
Specifically, a PTC erroneously introduced in a transcript and proximal to the translation start site leads to a more rapid interruption of the expensive process of protein synthesis and would be most efficiently recognized by the nonsense-mediated decay (NMD) system (van Hoof and Green 1996; Silva et al. 2006; Longman et al. 2007).
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Current knowledge indicates the importance of a maternal immune system, which most efficiently recognize and reject the fetal placenta as a foreign tissue, similar to an allogeneic transplant, as well as an immune inflammatory reaction during parturition.
Beginning with pioneering work in the 1980s, it has been demonstrated convincingly that major codons are more accurately and more efficiently recognized by the most abundant tRNA species [ 3- 10].
The portion of the multidimensional space selected around the known pre-miRNAs purports to include most structures which have the potential of being efficiently recognized by the cellular miRNA-processing machinery.
The protein was efficiently recognized by broadly neutralizing antibodies.
The malonyl-ACP is efficiently recognized by the E. coli keto-acyl synthase enzyme, FabH.
We showed that, in addition to CD8+, also CD4+ T cells expressing the transduced TCR CL3 efficiently recognized CaPo13 cells.
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