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Consistent with the subcutaneous model results, the addition of the cMET inhibitor INC280 to tumours pretreated with gemcitabine was the most efficient therapy.
When choosing the most efficient therapy for treating pediatric AR, it is possible to impact on the significant morbidity and economic burden associated with the disease.
The complex therapy used and the increasing number of patients make ovarian cancer a potentially expensive disease to treat, increasing concern to find the most efficient therapy (Berger et al, 1998).
Since we increased the use of hemodiafiltration with ultrapure dialysate, which is the most efficient therapy to reduce serum β2M levels, we expected a better conformity rate for β2M.
Since smoking cessation/replacement appears to be the most efficient therapy in smoking-related COPD, the models of early onset COPD can also be expected to be valuable tools for the development and testing of reduced risk products that may prevent COPD progression in a comparable manner as cessation does.
A pre-therapy scintigraphic approach with radiolabelled monoclonal antibodies (mAbs) may allow us to evaluate the presence of the target molecules in the inflammatory lesion, thus helping in the selection of the most efficient therapy and predicting therapy response; overall, they may provide a cost-effective solution [ 13].
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In the case of cancer, complete surgical resection of neoplasia remains one of the most efficient therapies while postsurgical minimal residual disease has a negative effect on long-term outcome[2].
Actually, the status of estrogen receptor (ER), progesterone receptor (PR), and human epidermal growth factor receptor type 2 (has2) has been used as predictive markers for identifying a high-risk phenotype and for selection of the most efficient therapies [ 13].
Advances in medical research have identified vascular endothelial growth factor (VEGF) as an important pathophysiological player in neovascular AMD and intraocular inhibition of VEGF as one of the most efficient therapies in medicine.
The most efficient photodynamic therapy (PDT) of the tumour was reached (day 20 tumour-free) when light exposure took place 2 h after injection of A1PcS2 (10 mg kg-1).
Complete surgical resection of neoplasia remains one of the most efficient tumor therapies.
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