Therefore, we should compare the most efficient screening programmes with primary HPV testing with the most efficient cytology-based programmes.
If a library of, say, 1000 compounds is to be screened against a protein target, it is most efficient to screen "cocktails" containing typically three to ten ligands, to reduce experimental time and protein consumption.
A whole-mouth method appears most efficient in screening for a large number of people.
One of the most efficient ways to screen for heart-disease risk is via tests for levels of low-density lipoprotein (LDL, or "bad") cholesterol.
The most efficient method of screening is likely to incorporate a step-wise process targeting those at highest risk as opposed to inviting everyone directly for a diagnostic test [ 10].
Finally, there is a need to establish the most efficient means of screening patients in primary care so as to minimise the workload for busy clinicians whilst also ensuring that appropriate patients receive brief intervention.
Trehalose octasulfate also showed promising antithrombotic property against IVC statis-induced venous thrombosis model in rats, which is one of the most efficient models for screening antithrombotic activity of the drugs.
Despite this considerable evidence-base, key questions remain unanswered including: the applicability of the evidence to routine practice; the most efficient strategy for screening patients; and the required intensity of brief intervention in primary care.
While mammography is the most efficient way to screen for primary breast cancers, the ability to spot primary breast lesions and metastases on routine CT scans is important, as this may lead to a diagnosis before the patient would have otherwise come to medical attention, and improve the accuracy of staging for patients with a breast cancer diagnosis.
To identify the most efficient and acceptable screening approach and tool to detect cases of hazardous and harmful drinking in routine primary care and also to evaluate the clinical impact and cost effectiveness of different models of BI aimed at reducing excessive drinking in routine primary health care.
