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Closer analysis and enrichment of the CD3+ subset phenotype (at either day 0 or day 8) revealed that the most efficient effector cell resided within the CD3+CD4+CD45RO+ memory subset, and more specifically within the effector memory population (CCR7-).
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Within the different DCs subtypes, myeloid DCs are also the most efficient antigen-presenting cells in the induction of naive, memory, effector and regulatory T-cell responses [1] [3].
In order to generate tumor-specific T cells with full effector function they first must undergo priming by dendritic cells (DCs), the antigen presenting cell (APC) most efficient at initiating potent CD8+ T-cell responses [4], [5].
Effector-triggered immunity (ETI) serves as the second line of defense and is one of the most efficient innate immunity in plants.
One of the most efficient workouts around.
Which route would be the most efficient?
TALENs (transcription activator-like effector nucleases), consisting of a custom TALE DNA binding domain fused to a nonspecific FokI cleavage domain, are one of the most efficient genome engineering methods developed to date.
We're the most efficient, efficient farmers.
AND, probably, the most efficient.
But what path is most efficient?
Strive for the simplest, most efficient, and most economical intervention.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com