In the last 20 years, the mortality rates by rotavirus have decreased in the more developed countries, but improvement in hygienic-healthy conditions has not modified the global incidence of the disease, and therefore, vaccination is the most efficacious measure to prevent this illness [ 6- 9].
Nowadays, a policy of elective single embryo transfer (eSET) is reported as the most efficacious measure of reducing the incidence of multiple pregnancies in ART (Wolner-Hanssen and Rydhstroem, 1998; Gerris et al., 1999, 2004; Van Royen et al., 1999; Gerris, 2000; Tiitinen et al., 2001; De Sutter et al., 2002, 2003; Gerris and Van Royen, 2005).
Contraception, condoms, and other means can mitigate the risks for unintended pregnancy and infection, but there is no disagreement that abstinence is the most efficacious preventive measure [ 18- 22].
Controversies remain about the most efficacious infection control measures to reduce the rate of hospital spread.
Concomitant CRT is among the most efficacious locoregional control measures, but at the same time, these recent trials reveal a shift in the pattern of failure towards distant disease especially in patients with advanced nodal stage.
A recently published meta-analysis assessing the relative efficacy of the currently available TNF-α inhibitors concluded that etanercept was the most efficacious treatment (as measured by American College of Rheumatology (ACR) response) compared with infliximab and adalimumab [ 13].
Results: For EP, all concentrations of lidocaine produced significant changes from baseline on 2 or 3 efficacy measures, however, the 4% concentration appeared to be the most efficacious when delivered by the EP method.
Simvastatin efficacy studies were reviewed to define dietary contexts within which simvastatin is most efficacious.
Death was Hartley's most efficacious muse.
Jack Kemp lauded his former aide: "It will be proven the most efficacious of all the reforms".
