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Figure 2 summarizes the 46 most efficacious (Level 1) strategies and their studied outcomes.
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Preventive headache agents may be most efficacious for patients with moderate levels of disability and for patients with high disability levels who attend all treatment appointments.
Some observations are possible, however, regarding levels of response seen with the most efficacious endocrine agents available today, albeit in less heavily pretreated patient populations.
The summation of these parallel effects generated an inverted U-shaped dose response, with the most efficacious dose around 10 8 to 10 9 M, coinciding with reported human exposure levels (Vandenberg et al. 2010).
The present study included patients with antithrombin levels in the range of 50 to 80%, which was anticipated to be the most efficacious for mortality according to the stratified subgroup analyses of our prospective multicenter study [ 24, 30].
Simvastatin efficacy studies were reviewed to define dietary contexts within which simvastatin is most efficacious.
Death was Hartley's most efficacious muse.
Jack Kemp lauded his former aide: "It will be proven the most efficacious of all the reforms".
Feinberg was by turns gentle and hostile, confiding and withholding, depending on what seemed most efficacious.
They will not be cured by our most efficacious drugs or slain with our sharpest swords.
In fact, methadone is one of the most, if not the most, efficacious of all the opioid analgesics for the treatment of human pain.
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