The probability of being ranked in the top three most efficacious classes was 96% for prostaglandin inhibitors, 63% for magnesium sulfate, 57% for calcium channel blockers, 33% for beta mimetics, 24% for nitrates, 14% for oxytocin receptor blockers, 13% for others, and 0% for placebo.
The most efficacious treatment class was prostaglandin inhibitors, which had an 83% probability of being the "best" class.
These studies included comparisons with olmesartan, which itself appears to be one of the most efficacious agents in the class 21,22.
As a class, bisphosphonates are the most efficacious anti-resorptive agents currently available for bone.
There does not appear to be a clear consensus as to which class of antidepressant medication is most efficacious for depressed patients exhibiting melancholic features.
Drugs with multiple classes of action rather than specific class action, such as amiodarone, are the most efficacious in treating AF, but many drugs are limited to low-risk patients because of concerns regarding proarrhythmia.
Within this pharmacological class we selected thioridazine, which is most efficacious and least toxic, when used as an antipsychotic drug.
For medical conversion of recent-onset AF, class IC antiarrhythmic drugs, administered as an oral bolus, have been demonstrated to be the most efficacious pharmacologic conversion agents.
Simvastatin efficacy studies were reviewed to define dietary contexts within which simvastatin is most efficacious.
Death was Hartley's most efficacious muse.
