Sentence examples for most effective vectors from inspiring English sources

The two most effective vectors (ZnT8-3 and ZnT8-4) were then transfected in combination under puromycin selection (2 µg/ml) to generate a pooled stable cell line, and were compared to INS-1 cells stably transfected (in parallel) with empty shRNA vector or with GFP-directed shRNA.

The seven most effective vectors almost exclusively generated short deletions, whereas the lower efficiency vectors contained more insertions/SNPs (Additional file 2).

The most effective vectors in use are mostly viral vectors owing to their practical advantages such as ease of construction, good production titer, and high transgene expression.

We decided to use an adenovirus to transduce the 5HREp-BCD gene into tumour cells in vivo, because the adenovirus is one of the most effective vectors with which to accomplish trans-gene expression.

LLINs and IRS were developed against the most effective vectors, which share the attributes of feeding late at night and being anthropophilic (preferring to feed on humans), endophagic (preferring to feed indoors), and endophilic (preferring to rest indoors) (Lengeler 2004; Tanser 2007).

To decrease the apoptosis of bovine fibroblast cells, we construsted specific short hairpin (shRNA) expression vector encoding shRNA targeting Bax gene to screen the most effective vector.

This disparity indicates the most effective vector control delivery strategies may vary geographically.

Although these investigations demonstrated that the general strategy of gene therapy for CF is hopeful, they also showed that the efficiency of even the presently most effective vector system, adenovirus, is still disappointingly low [ 2- 9].

Therefore, although some problems such as the most effective vector to employ for humans remain unresolved, in the future our method may have useful applications not only for treatment of autoimmune diseases but also for management of transplant rejection and GVHD in humans.

The most effective viral vector reported to date is a recombinant adeno-associated virus vector expressing G6Pase-α directed by the native G6PC promoter/enhancer that effectively extends the lifespan of mice, corrects the metabolic abnormalities and even prevents the development of hepatocellular adenoma (HCA) (Yiu et al., 2010; Lee et al., 2012).

The world's most effective malaria vector mosquito species, Anopheles gambaie thrives in sub-Saharan Africa where human populations are expanding and ecological conditions are becoming more favorable for malaria parasite transmission.