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The main objective is to provide a tool for identifying the most effective risk reducing measures.
Since osteoporosis is a multi-factorial disease, combination of risk factors with BMD produces the most effective risk assessment for MOF as opposed to assessment of any risk factor alone [ 7].
The basic logic of this tailoring is shown in Figure 2; more detailed content is provided in Additional File 2. In brief, messages were first tailored based on patients' intentions to start one or more of the most effective risk reducing strategies (e.g. take aspirin, cholesterol medication, hypertension medication, or stop smoking).
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Prophylactic surgery (bilateral mastectomy, bilateral salpingo-oophorectomy or a combination of both procedures) has proved to be the most effective risk-reducing strategy.
While prophylactic mastectomy is the most effective risk-reducing therapy, many carriers would opt for heightened surveillance instead, given a sufficient degree of confidence in the opportunity for early detection [ 17].
While it is still unclear whether and under which circumstances visual presentation is most effective in risk communication (4, 5), we chose to present a reference class of 100 people, since some evidence was available for this (13 , 24.
Once these MRA models gain more acceptance, they may facilitate scenario testing to determine which control points may be most effective in reducing risks and which risk-driving attributes should be specifically considered and minimized during the development of novel antibiotics.
At least two studies have shown that the most preferred risk formats are not necessarily the same as the most effective formats for risk communication in medical decision making [ 13, 14].
The treatment using 10 g P kg− 1 appeared to be most effective for overall risk reduction.
As many volcanoes and volcanic regions around the world are already heavily populated, the most effective means of risk reduction will be to identify the most hazardous areas and evacuate the population from the danger zone prior to an eruption (Marzocchi and Woo 2007, Lindsay et al. 2011, Sandri et al. 2012).
We aimed to determine which modality of lifestyle intervention was most effective at reducing risk of diabetes and/or CVD.
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