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Our findings suggest that people with dementia are very unlikely to receive varenicline, one of the most effective cessation therapies, from their GP.
One reason for the low success is that many quitting attempts are unplanned so that the most effective cessation aids may not be used [ 8].
Although nearly half of all smokers in the United Kingdom try to stop every year, only 2-32-3%cceed. 1 One reason for the low success is that many quit attempts are unplanned 2 so that the most effective cessation aids may not be used.
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Ultimately, it could discourage people from using the most effective smoking cessation treatment.
PAS (Personal Advice in Stopping smoking) combines two of the most effective smoking cessation interventions: multiple computer tailoring and tailored counselling by a practice nurse in the general practice.
Varenicline is probably the most effective smoking cessation pharmacotherapy, but is less widely used than nicotine replacement therapy.
The most effective smoking cessation therapy in non-pregnant smokers is a combination of behavioural support and pharmacotherapy with either nicotine replacement therapy (NRT) [ 5] or bupropion [ 6].
Varenicline is a partial agonist that binds at the nicotinic α4β2 receptor, and it seems to be the most effective smoking cessation product currently available.
Table 1 shows the results for the least and most effective smoking cessation interventions included in the NICE exercise together with a mid-range intervention.
Previous systematic reviews addressing smoking cessation in people with COPD have concluded that a combination of stop smoking medication (SSM) and non-pharmacological approaches offers the most effective smoking cessation intervention for people with COPD.
Combining behavioural support and pharmacotherapy is most effective for smoking cessation and recommended in clinical guidelines.
Write better and faster with AI suggestions while staying true to your unique style.
Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com