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"most effective avenue" is correct and usable in written English.
You can use it to describe the most efficient or successful way to achieve a goal. For example, "The school district is taking the most effective avenue to reduce student absences by implementing a reward system for students who have perfect attendance."
Exact(4)
The parental role is the most effective avenue for change.
While media publicity is perhaps the most visible, it is not necessarily the most effective avenue for science communication.
Participants reported that the broad reach and subliminal nature of advertising on television or radio would make those media the most effective avenue for disseminating information on STDs and available services to youth (Table 4).
Detection rates of psychological problems are not necessarily associated with GP level of training in mental health or adolescent health [ 7], suggesting that further GP training in recognising mental health disorders may not be the most effective avenue for increasing detection rates.
Similar(56)
Within the cannabis space, social media influencers and well-managed, strategic page campaigns can be some of the most effective avenues to reach consumers.
Cooperation among women and adolescents, like Doly and her friends, is one of the most effective avenues for womens empowerment in the community and in the household, and can have long-lasting benefits for women.
Had Bush not been such a well-funded wimp who opened the door to a critique of his brother's presidency, Trump wouldn't have had the avenue to launch his most effective attacks on the establishment.
Most effective ads are emotional.
At present the most effective is economic.
Pesticides are the most effective means.
Prevention was the most effective approach.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com