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Relative to several other toll-like receptor (TLR) agonists, we found polyinosinic:polycytidylic acid (poly IC) to be the most effective adjuvant for Th1 CD4 T cell responses to a dendritic cell (DC -targeted HIV gag protein vaccine in mice.
Among all these adjuvants, PLGA was found to be the most effective adjuvant [ 16].
Tamoxifen is one of the most effective adjuvant breast cancer therapies available.
Future studies will determine whether these genomic signatures can be applied to early breast cancer patients to identify the most effective adjuvant endocrine treatment.
Choosing the most effective adjuvant chemotherapy regimen up front should thus lead to a further reduction in disease recurrences and, accordingly, to increased survival of the patients.
Patients with HR+ breast cancer considered eligible for adjuvant chemotherapy because of their increased risk for relapse should also be candidates for the most effective adjuvant endocrine strategy [ 100].
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Composed of mineral oil, surfactant and mycobacteria, FCA has always been considered to be one of the most effective adjuvants.
Having demonstrated that TSLP was the most effective cytokine adjuvant of those tested, we sought to compare it with CT a mucosal adjuvant commonly used in murine studies 3, 5. Mice were immunised three times i.n. with 10 μg gp140 alone or with 5 μg TSLP or CT.
Thus far, ISA206 is considered the most effective oil adjuvant in FMD vaccines for protecting animals against infection.
In pancreatic cancer, chemotherapy appears to be most effective in the adjuvant setting.
Which approach is the most effective in the adjuvant setting in postmenopausal women: up-front aromatase inhibitors, sequential, or extended after five years of tamoxifen?
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