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Of the three mutations, Smc1 F584R has the most drastic binding defect.
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Thioredoxin M-type, chloro-plastic precursor, and glycine-rich RNA-binding, abscisic acid-inducible protein exhibited the most drastic changes at the protein level, but their expression levels were not similar to their protein abundances.
The most drastic has….
Strategically, divesting cable would be the most drastic move.
It is the most drastic treatment we have for obesity.
But the most drastic changes would come internally.
It is one of society's most drastic interventions".
He ruled out the most drastic option – suicide – but the next most drastic alternative came to him immediately.
On September 8th Gordon Brown, a former prime minister, outlined the most drastic plan yet.
And it's always Mr. Right who exerts the most drastic manipulation of all.
Critics are calling it the most drastic nationalization of private assets since Soviet times.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

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CEO of Professional Science Editing for Scientists @ prosciediting.com