Sentence examples for most dramatic inhibition from inspiring English sources

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"It was the most dramatic inhibition of membrane repair that we had ever seen," says cellular biologist and co-author Paul McNeil of the Medical College of Georgia in Augusta.

Hence, the most dramatic inhibition of EGFR internalization occurred at 2 min with 60% being internalized in control cells compared with 20% being internalized in cells expressing Tom1L1/Y460F, Tom1L1/Y392F or Tom1L1/Y460F SH3.

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However, the Y808A, Y808E and Y808S mutants were far less sensitive to S1P treatment, with the Y808E mutant showing the most dramatic resistance to inhibition. Figure 4(B) shows how the Tyr mutations affect GC-B inhibition by PMA and Na3VO4.

Consequently, rate−saturation plots of rates of ATase or NRII activities versus α-ketoglutarate concentration are biphasic for reactions controlled by PII, with the PII effect (activation or inhibition) being most dramatic at low concentrations of α-ketoglutarate and reduced at higher concentrations of α-ketoglutarate (4, 5, 17, 19).

For the third point mutant (C289G), which displayed the most dramatic aggregative phenotype, combined kinase inhibition led to a decrease in the number of cells displaying large perinuclear aggregates, indicating beneficial effects of such inhibitor treatment in modulating the profound aggregation even of this pathogenic mutant.

The initial and most dramatic symptom of Al toxicity is rapid inhibition of root elongation, and thus root relative elongation rate has served as a typical marker of levels of Al toxicity and tolerance in plants (Chandran et al. [2008]; Pan et al. [2001]; Reid et al. [1996]).

The most dramatic dose-dependent effect was on the CFU-MK growth inhibition assessed in fibrin clots that reached 62.5% at 50 nM and more than 90% at 100 nM.

In summary, our results indicated that knockdown of each of the three candidate genes resulted in reduced cell proliferation rates, with inhibition of VCP and DCTN3 causing the most dramatic reductions in SCC-9 cell growth (Fig. 3A D).

The most dramatic change is in the Ki,ToMOD, which reflects much weaker ToMOD inhibition at high concentrations of ToMOC.

C271Y had the most dramatic effects, resulting in poor protein expression, aberrant localization to the nucleus and dominant-negative inhibition of neurite outgrowth.

The most dramatic was religion.

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