Sentence examples for most downstream protein from inspiring English sources

Equation 6 describes the rate of change of Ime2, the most downstream protein in the model.

Ime2 is used as the model readout for sporulation phenotypes because it is the most downstream protein that reflects changes in all others in the pathway.

In the context of yeast meiosis, feedback loops linking early proteins may be responsible for distinct sporulation efficiencies, traced by steady state levels of Ime2, the most downstream protein in the model.

On the contrary, most downstream proteins involved in autophagy were detected in P. falciparum and appear to be functional.

The p21 is the most important downstream protein regulated by the activated p53, which can directly inhibit cell growth, increase apoptosis, and cause cell cycle arrest at S phase [ 29].

One of the most important downstream proteins affected by mTOR is hypoxia-induced factor 1 α.

Although we do see a slight increase in the active XBP1 protein, most downstream XBP1 targets do not respond by increases in mRNA abundance.

Rad51 is the most downstream of these four proteins and is directly involved in HR.

XIAP (X-linked inhibitor of apoptosis protein) is the most downstream inhibitor of apoptosis and is considered the most potent and ubiquitous caspase inhibitor among the members of the IAP (inhibitor of apoptosis protein) family.

The loss-of-function PAR alleles have suggested a complicated hierarchy; however, all of the PAR proteins are necessary for proper PAR-1 localization, suggesting that PAR-1 is the most downstream effector of the other PAR proteins (Fig. 2) (Baas et al. 2004b).

However, most downstream processing methods mainly rely on expensive chromatographic approaches to purify the fusion proteins, which lower the overall protein yield substantially (Azevedo et al. 2009).