Sentence examples for most downregulated transcripts from inspiring English sources

Our finding that the most downregulated transcripts contain a short 3'UTR is possibly linked to the fact that most of these transcripts represent housekeeping genes [42].

Egr2, an immediate early gene with an unknown role in the heart, was diminished −1.6 fold, and was also among the ten most downregulated transcripts.

We noted that the most downregulated transcripts were the immediate early response genes, early growth response 1 (Egr1) (−2.5 fold, the most downregulated transcript in the entire array) and FBJ osteoscarcoma oncogene (Fos) (−1.9 fold, the second most downregulated transcript) (Fig. 5C).

At E13.5, these genes represent 6 of the 15 most downregulated transcripts identified by microarray analysis.

Five of the most downregulated transcripts identified in the microarray analysis were unidentified cDNA clones (Affymetrix IDs 1436320_at, 1448057_at, 1443755_at, 1429730_at and 1453066_at; Accessions [GenBank: W45978], [GenBank: BI202412], [GenBank: BE457721], [GenBank: AK007409] and [GenBank: BI320076] respectively).

IL-1B was among the most significantly downregulated transcripts.

Interestingly Fxyd5, which was the most prominent downregulated transcript by NO (18-folds) was significantly relieved of this effect when subjected to hypoxia plus NO.

Subsequently, ordering transcripts based on PPLR produces a ranking of most probable upregulated and downregulated transcripts.

Most of the strongly downregulated transcripts were related to photosynthesis, photorespiration, and metabolism of amino acids and carbohydrates.

In the present study we identified the most up- and downregulated transcripts, which are associated to a network of putative interactions.

This regulation is highly dynamic, with the maximum regulation for most up- and downregulated transcripts occurring after 30 minutes of TNFα treatment, with a return to basal state at 120 minutes.